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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLEKHM1 All Species: 16.36
Human Site: Y148 Identified Species: 40
UniProt: Q9Y4G2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4G2 NP_055613.1 1056 117443 Y148 E Q A R L H E Y Y Q P T A L L
Chimpanzee Pan troglodytes XP_001140498 1061 118011 Y148 E Q A R L H E Y Y Q P T A L L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548048 1056 117749 Y140 E P A R L C E Y Y Q P T A L L
Cat Felis silvestris
Mouse Mus musculus Q7TSI1 1074 118516 Y147 E P A R L C E Y Y Q P T A L L
Rat Rattus norvegicus Q5PQS0 1059 117490 Y147 E P A R L C E Y Y Q P T A L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507582 964 103304 F121 L D P E E A E F L L S F L Q G
Chicken Gallus gallus NP_001026095 1005 111261 V129 L S L N D G L V E C Y L K L L
Frog Xenopus laevis Q08AW4 748 85595
Zebra Danio Brachydanio rerio NP_001082872 845 95085
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395844 660 73853
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 N.A. 85 N.A. 82.7 83.2 N.A. 35.3 60.1 24.3 37.9 N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: 100 99.1 N.A. 89.1 N.A. 87.3 88.3 N.A. 47.9 73.1 41.1 53.8 N.A. N.A. 35.6 N.A. N.A.
P-Site Identity: 100 100 N.A. 86.6 N.A. 86.6 86.6 N.A. 6.6 13.3 0 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 100 N.A. 86.6 N.A. 86.6 86.6 N.A. 13.3 13.3 0 0 N.A. N.A. 0 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 50 0 0 10 0 0 0 0 0 0 50 0 0 % A
% Cys: 0 0 0 0 0 30 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 50 0 0 10 10 0 60 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 20 0 10 0 50 0 10 0 10 10 0 10 10 60 60 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 30 10 0 0 0 0 0 0 0 50 0 0 0 0 % P
% Gln: 0 20 0 0 0 0 0 0 0 50 0 0 0 10 0 % Q
% Arg: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 50 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _